colistimethate and Neomycin Interactions

You searched for interactions between

• colistimethate
• Neomycin (neomycin)

Interaction(s) found:

neomycin and colistimethate (Major Drug-Drug)

GENERALLY AVOID: The combination of a polypeptide antibiotic and an aminoglycoside increases the risk of respiratory paralysis and renal dysfunction. The mechanism of this interaction is not known.

MANAGEMENT: This combination should be avoided concurrently or sequentially.