Drug interactions between Colestid and levothyroxine
| Results for the following 2 drugs: |
|---|
| Colestid (colestipol) |
| levothyroxine |
Interactions between your selected drugs
levothyroxine ↔ colestipol
Applies to:levothyroxine and Colestid (colestipol)
ADJUST DOSING INTERVAL: Bile acid sequestrants may bind to and decrease the gastrointestinal absorption of thyroid hormones. There have been isolated reports of worsening hypothyroidism and increased TSH levels following the addition of cholestyramine in patients receiving thyroid replacement therapy.
MANAGEMENT: Thyroid hormone preparations and bile acid sequestrants should be administered at least 4 hours apart. Close clinical and laboratory monitoring of thyroid function is recommended during coadministration, since adjusting the dosing interval may not completely prevent the interaction.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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