Drug interactions between Cholestyramine Light and Miradon
| Results for the following 2 drugs: |
|---|
| Cholestyramine Light (cholestyramine) |
| Miradon (anisindione) |
Interactions between your selected drugs
cholestyramine ↔ anisindione
Applies to:Cholestyramine Light (cholestyramine) and Miradon (anisindione)
MONITOR: Cholestyramine may decrease the absorption and increase the elimination of warfarin or other oral anticoagulants. Anticoagulant effect may be reduced. However, cholestyramine also may impair vitamin K absorption, and the anticoagulant effect of warfarin may be enhanced in some patients. Starting or stopping cholestyramine in the presence of chronic oral anticoagulant therapy may lead to altered PT or INR.
MANAGEMENT: Warfarin or other oral anticoagulants should be administered at least one hour before or four to six hours after cholestyramine. The INR or PT should be closely monitored. Patients should be advised to promptly report any signs of bleeding (e.g., pain, swelling, headache, dizziness, weakness, vaginal bleeding, nosebleeds, bleeding of gums from brushing, unusual bleeding or bruising, red or brown urine, or red or black stools) or clots (e.g. chest pain, shortness of breath, sudden loss of vision, or pain, redness or swelling in an extremity).
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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