Drug interactions between Chloromycetin and Elidel
Results for the following 2 drugs: |
|
|---|---|
| Chloromycetin (chloramphenicol) | |
| Elidel (pimecrolimus topical) | |
Interactions between your selected drugs
chloramphenicol ⇔ pimecrolimus
Applies to: Chloromycetin (chloramphenicol) and Elidel (pimecrolimus topical)
Theoretically, coadministration with CYP450 3A inhibitors may increase the plasma concentrations of pimecrolimus, which has been shown in vitro to undergo metabolism by this subfamily of hepatic microsomal enzymes. Although clinically significant drug interactions are not expected due to minimal systemic absorption of topically administered pimecrolimus, the possibility cannot be ruled out. The manufacturer recommends caution in patients with widespread and/or erythrodermic disease.
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