Drug interactions between Chloromycetin Sodium Succinate and Gesticare DHA
| Results for the following 2 drugs: |
|---|
| Chloromycetin Sodium Succinate (chloramphenicol) |
| Gesticare DHA (multivitamin, prenatal) |
Interactions between your selected drugs
chloramphenicol ↔ multivitamin, prenatal
Applies to:Chloromycetin Sodium Succinate (chloramphenicol) and Gesticare DHA (multivitamin, prenatal)
MONITOR: Chloramphenicol can cause bone marrow depression and inhibit red blood cell maturation, which may interfere with the therapeutic effects of iron or vitamin B12 in the treatment of anemia. In a group of 22 patients receiving iron dextran for iron deficiency anemia, 10 patients who also received chloramphenicol had inadequate hematologic response to the iron therapy. Four patients receiving vitamin B12 for pernicious anemia were also unresponsive to the B12 therapy while being treated with chloramphenicol. Reversible bone marrow depression is more likely to occur at higher chloramphenicol dosages that produce serum levels of 25 mcg/mL or greater.
MANAGEMENT: Patients with preexisting anemia should preferably not receive chloramphenicol due to the drug's depressive effect on bone marrow and reticulocytes. If use is unavoidable, the lowest effective dosage of chloramphenicol should be given. Hematologic response to iron or vitamin B12 therapy should be closely monitored.
See also...
- Chloromycetin Sodium Succinate Drug Interactions
- Chloromycetin Sodium Succinate General Consumer Information
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. Multum's drug information does not endorse drugs, diagnose patients, or recommend therapy. Multum's drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2012 Multum Information Services, Inc. The information in contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
