Drug interactions between Cervidil and Pitocin
| Results for the following 2 drugs: |
|---|
| Cervidil (dinoprostone topical) |
| Pitocin (oxytocin) |
Interactions between your selected drugs
oxytocin ↔ dinoprostone
Applies to:Pitocin (oxytocin) and Cervidil (dinoprostone topical)
ADJUST DOSING INTERVAL: Prostaglandins, especially those of the E type, may potentiate the uterine response to oxytocin and increase the risk of uterine hyperstimulation and rupture. The mechanism of interaction is unknown.
MANAGEMENT: Infusion of oxytocin should not be started until at least 6 to 12 hours after the use of dinoprostone vaginal gel (6 to 12 hours recommended for Prepidil Gel and 12 to 24 hours for Prostin E2 Vaginal Gel) or at least 30 minutes after the removal of dinoprostone vaginal insert.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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