Drug Interactions

Drug interactions between Cervidil and Pitocin

Results for the following 2 drugs:

Cervidil (dinoprostone topical)
Pitocin (oxytocin)

Interactions between your selected drugs

oxytocin ⇔ dinoprostone

Applies to: Pitocin (oxytocin) and Cervidil (dinoprostone topical)

ADJUST DOSING INTERVAL: Prostaglandins, especially those of the E type, may potentiate the uterine response to oxytocin and increase the risk of uterine hyperstimulation and rupture. The mechanism of interaction is unknown.

MANAGEMENT: Infusion of oxytocin should not be started until at least 6 to 12 hours after the use of dinoprostone vaginal gel (6 to 12 hours recommended for Prepidil Gel and 12 to 24 hours for Prostin E2 Vaginal Gel) or at least 30 minutes after the removal of dinoprostone vaginal insert.

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