Drug interactions between Celexa and Prilosec
Results for the following 2 drugs: |
|
|---|---|
| Celexa (citalopram) | |
| Prilosec (omeprazole) | |
Interactions between your selected drugs
omeprazole ⇔ citalopram
Applies to: Prilosec (omeprazole) and Celexa (citalopram)
MONITOR: CYP450 2C19 is one of the two primary enzymes responsible for the metabolism of citalopram. Concomitant use of citalopram with drugs which inhibit CYP450 2C19 enzymes may decrease the clearance of citalopram. Caution is advised that higher citalopram blood levels may exist if citalopram is to be administered with a enzyme inhibitor.
MANAGEMENT: Dosage adjustments as well as clinical and laboratory monitoring may be appropriate whenever an enzyme inhibitor is added to or withdrawn from therapy. Close monitoring is recommended for signs and symptoms of excessive serotonergic activity such as CNS irritability, altered consciousness, confusion, myoclonus, ataxia, abdominal cramping, hyperpyrexia, shivering, pupillary dilation, diaphoresis, hypertension, and tachycardia.
See also...
Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. Multum's drug information does not endorse drugs, diagnose patients, or recommend therapy. Multum's drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2009 Multum Information Services, Inc. The information in contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
