Drug interactions between Catapres and Lantus
| Results for the following 2 drugs: |
|---|
| Catapres (clonidine) |
| Lantus (insulin glargine) |
Interactions between your selected drugs
clonidine ↔ insulin glargine
Applies to:Catapres (clonidine) and Lantus (insulin glargine)
MONITOR: Clonidine may diminish the physiological response to hypoglycemia induced by insulin and/or oral hypoglycemic agents (i.e., insulin secretagogues such as sulfonylureas and meglitinides). Clonidine inhibits the release of catecholamines, which are responsible for recovery of normal blood glucose levels and symptoms of hypoglycemia such as tremor, sweating, tachycardia, and blood pressure changes. In normal and hypertensive individuals, response to insulin-induced hypoglycemia has been shown to decrease significantly during administration of clonidine 0.45 to 0.9 mg daily. However, clonidine has also been reported to elevate plasma blood glucose and cause hyperglycemia.
MANAGEMENT: Patients should be instructed about the need for regular monitoring of blood glucose levels and be aware that certain symptoms of hypoglycemia such as tremors, sweating, and tachycardia may be reduced or absent during treatment with clonidine.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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