Drug interactions between Cartia XT and chlorthalidone/clonidine
| Results for the following 2 drugs: |
|---|
| Cartia XT (diltiazem) |
| chlorthalidone/clonidine |
Interactions between your selected drugs
clonidine ↔ diltiazem
Applies to:chlorthalidone/clonidine and Cartia XT (diltiazem)
MONITOR: Coadministration of clonidine with agents known to affect sinus node function of AV nodal conduction may be associated with significantly reduced heart rate. Sinus bradycardia and complete AV block resulting in hospitalization and pacemaker insertion have been reported during the concomitant use of clonidine and diltiazem or verapamil. The exact mechanism of interaction is unknown. However, these drugs individually have been associated with AV node dysfunction and may have additive effects during coadministration.
MANAGEMENT: Heart rate and blood pressure should be closely monitored in patients receiving clonidine in combination with agents known to affect sinus node function of AV nodal conduction such as digitalis and certain calcium channel blockers.
See also...
- Cartia XT Drug Interactions
- Cartia XT 24-Hour Sustained-Release Beads Capsules General Consumer Information
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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