Drug interactions between carbamazepine and Zyban
Results for the following 2 drugs: |
|
|---|---|
| carbamazepine | |
| Zyban (bupropion) | |
Interactions between your selected drugs
carbamazepine ⇔ bupropion
Applies to: carbamazepine and Zyban (bupropion)
MONITOR: Bupropion is extensively metabolized by hepatic microsomal enzymes, primarily CYP450 2B6. Theoretically, plasma concentrations and pharmacologic effects of bupropion may be diminished when given concurrently with some CYP450 enzyme inducers.
MANAGEMENT: Pharmacologic response to bupropion should be monitored more closely whenever a CYP450 inducer is added to or withdrawn from therapy, and the bupropion dosage adjusted as necessary.
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