calcium-disodium-versenate and Posicor Interactions

Interactions between calcium-disodium-versenate(edetate calcium disodium) and Posicor (mibefradil)

edetate calcium disodium and mibefradil (Moderate Drug-Drug)

MONITOR: Calcium-containing products may decrease the effectiveness of calcium channel blockers by saturating calcium channels with calcium. Calcium chloride has been used to manage acute severe verapamil toxicity.

MANAGEMENT: Management consists of monitoring the effectiveness of calcium channel blocker therapy during coadministration with calcium products.