calcium-carbonate and Alophen Interactions

Interactions between calcium-carbonate(calcium carbonate) and Alophen (bisacodyl)

calcium carbonate and bisacodyl (Moderate Drug-Drug)

ADJUST DOSING INTERVAL: By increasing gastric pH, antacids may reduce the resistance of the enteric coating of bisacodyl tablets, resulting in earlier release of bisacodyl and gastric irritation and dyspepsia.

MANAGEMENT: The administration of antacids and bisacodyl should be separated by at least one hour.