Drug interactions between Calcium 600 D and hydroxychloroquine
| Results for the following 2 drugs: |
|---|
| Calcium 600 D (calcium/vitamin d) |
| hydroxychloroquine |
Interactions between your selected drugs
calcium carbonate ↔ hydroxychloroquine
Applies to:Calcium 600 D (calcium/vitamin d) and hydroxychloroquine
ADJUST DOSING INTERVAL: Concomitant administration of antacids, kaolin, or magnesium compounds may reduce the bioavailability of chloroquine. The proposed mechanism is adsorption of chloroquine by the antacid or kaolin. Decreased dissolution of chloroquine in the presence of magnesium has also been reported. Chloroquine absorption may be reduced by as much as 30% to 53%. The efficacy of chloroquine may be decreased, which could potentially result in therapeutic failure. Hydroxychloroquine may theoretically also be affected.
MANAGEMENT: It is recommended that the administration of these preparations and chloroquine or hydroxychloroquine be separated by at least 4 hours.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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