calan and Cordarone i v Interactions

Interactions between calan(verapamil) and Cordarone i v (amiodarone)

amiodarone and verapamil (Major Drug-Drug)

MONITOR CLOSELY: Amiodarone and diltiazem or verapamil may have additive pharmacodynamic effects when administered concurrently. Sinus arrest, reduced myocardial contractility, and hypotension could result.

MANAGEMENT: The patient's hemodynamic and electrocardiographic status should be closely monitored, especially during amiodarone loading.