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Drug Interactions between Cafatine and mixed grass pollens allergen extract

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

ergotamine mixed grass pollens allergen extract

Applies to: Cafatine (caffeine / ergotamine) and mixed grass pollens allergen extract

Using mixed grass pollens allergen extract together with ergotamine may not be advisable. Immunotherapy with mixed grass pollens allergen extract can sometimes cause severe, even potentially life-threatening allergic reactions that require emergency treatment with epinephrine, and medications like ergotamine can interfere with the body's response to epinephrine and significantly reduce its effectiveness. Talk to your doctor if you have any questions or concerns. Stop using mixed grass pollens allergen extract, administer epinephrine, and seek immediate medical attention if signs and symptoms of an allergic reaction develop such as trouble breathing, swallowing, or speaking; throat tightness or swelling; dizziness, lightheadedness, or fainting; rapid or weak heartbeat; severe stomach cramps or pain; vomiting or diarrhea; and/or severe flushing or itching. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

ergotamine food

Applies to: Cafatine (caffeine / ergotamine)

Grapefruit juice may increase the blood levels of certain medications such as ergotamine. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with ergotamine. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Moderate

mixed grass pollens allergen extract food

Applies to: mixed grass pollens allergen extract

Consuming food or beverage during or immediately after using mixed grass pollens allergen extract may reduce the amount of allergen extract available for absorption from tissues under the tongue into the blood stream. Food or beverage should not be taken with, or for at least 5 minutes after, using mixed grass pollens allergen extract. Use of alcohol with mixed grass pollens allergen extract may increase the risk and severity of allergic reactions that can sometimes occur during treatment with mixed grass pollens allergen extract. Potentially life-threatening or fatal reactions may occur. Talk to your doctor if you have any questions or concerns. Stop using mixed grass pollens allergen extract, administer epinephrine, and seek immediate medical attention if signs and symptoms of an allergic reaction develop such as trouble breathing, swallowing, or speaking; throat tightness or swelling; dizziness, lightheadedness, or fainting; rapid or weak heartbeat; severe stomach cramps or pain; vomiting or diarrhea; and/or severe flushing or itching. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

ergotamine food

Applies to: Cafatine (caffeine / ergotamine)

Nicotine may increase the effects of ergotamine in narrowing the blood vessels and decreasing blood flow. A severe decrease in blood flow to the brain and other parts of the body can lead to dangerous side effects. Contact your doctor immediately if you experience coldness, paleness, discoloration, numbness, tingling, or pain in your hands or feet; muscle pain or weakness; severe or worsening headache; blurred vision; severe abdominal pain; chest pain; or shortness of breath while using these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

caffeine food

Applies to: Cafatine (caffeine / ergotamine)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.