cabergoline and Antinaus 50 Interactions

Interactions between cabergoline and Antinaus 50 (promethazine)

promethazine and cabergoline (Moderate Drug-Drug)

GENERALLY AVOID: Agents with central antidopaminergic activity such as phenothiazines, neuroleptics and metoclopramide may antagonize the pharmacologic effects of dopamine agonists. In addition, the central nervous system depressant and hypotensive effects of these agents may be additively or synergistically increased when taken together.

MANAGEMENT: Concomitant use of dopamine agonists with antidopaminergic agents should generally be avoided. If coadministration is necessary, patients should be alerted to the possibility of excessive drowsiness and monitored for potentially diminished therapeutic response to their dopaminergic therapy. Patients treated for Parkinson's disease should generally avoid antidopaminergic agents, particularly phenothiazines and older neuroleptic agents, since these agents may cause extrapyramidal reactions.