byetta and Prinivil Interactions

Interactions between byetta(exenatide) and Prinivil (lisinopril)

lisinopril and exenatide (Minor Drug-Drug)

Administration of exenatide (10 mcg twice daily) to patients with mild to moderate hypertension stabilized on lisinopril (5 to 20 mg/day) did not alter steady-state peak plasma concentration (Cmax) or systemic exposure (AUC) of lisinopril. The time to reach peak plasma lisinopril concentration (Tmax) was delayed by 2 hours. There were no changes in 24-hour mean systolic and diastolic blood pressure.