Drug interactions between Byetta and Glucovance
| Results for the following 2 drugs: |
|---|
| Byetta (exenatide) |
| Glucovance (glyburide/metformin) |
Interactions between your selected drugs
glyburide ↔ exenatide
Applies to:Glucovance (glyburide/metformin) and Byetta (exenatide)
ADJUST DOSE: Coadministration of a glucagon-like peptide-1 (GLP-1) receptor agonist with an insulin secretagogue (e.g., sulfonylurea, meglitinide) may potentiate the risk of hypoglycemia.
MANAGEMENT: A lower dosage of the insulin secretagogue may be required when used in combination with a GLP-1 receptor agonist such as exenatide or liraglutide. Blood glucose should be monitored closely, and patients should be counseled to recognize symptoms of hypoglycemia such as headache, dizziness, drowsiness, nausea, tremor, weakness, hunger, excessive perspiration, and palpitations. If hypoglycemia occurs, patients should initiate appropriate remedial therapy immediately and contact their physician. Patients should be advised to take precautions to avoid hypoglycemia while driving or operating hazardous machinery.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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