Drug interactions between bumetanide and Coumadin
Results for the following 2 drugs: |
|
|---|---|
| bumetanide | |
| Coumadin (warfarin) | |
Interactions between your selected drugs
warfarin ⇔ bumetanide
Applies to: Coumadin (warfarin) and bumetanide
Some loop diuretics may displace warfarin or other oral anticoagulants from plasma protein binding sites. Plasma warfarin concentrations and warfarin effects may be increased. Data are available for furosemide and ethacrynic acid only. This interaction appears to be of minor clinical importance. Close monitoring of the INR is recommended, particularly if diuretic dosage must be high. Patients should be advised to promptly report any signs of bleeding to their physician, including pain, swelling, headache, dizziness, weakness, prolonged bleeding from cuts, increased menstrual flow, vaginal bleeding, nosebleeds, bleeding of gums from brushing, unusual bleeding or bruising, red or brown urine, or red or black stools.
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