Drug interactions between Budeprion and Commit
Results for the following 2 drugs: |
|
|---|---|
| Budeprion (bupropion) | |
| Commit (nicotine) | |
Interactions between your selected drugs
bupropion ⇔ nicotine
Applies to: Budeprion (bupropion) and Commit (nicotine)
MONITOR: The concomitant use of bupropion and nicotine replacement for smoking cessation may increase the risk of hypertension. In a clinical study (n=250), 6.1% of patients who used sustained-release bupropion with nicotine transdermal system developed treatment-emergent hypertension, compared to 2.5% of patients treated with bupropion alone, 1.6% treated with nicotine alone, and 3.1% treated with placebo. Three patients in the bupropion plus nicotine group and one patient in the nicotine-only group discontinued treatment due to hypertension. The majority had evidence of preexisting hypertension.
MANAGEMENT: Blood pressure monitoring is recommended for patients concomitantly using bupropion and nicotine replacement for smoking cessation.
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