Drug interactions between benztropine and Zoloft
| Results for the following 2 drugs: |
|---|
| benztropine |
| Zoloft (sertraline) |
Interactions between your selected drugs
benztropine ↔ sertraline
Applies to:benztropine and Zoloft (sertraline)
MONITOR: Delirium has been observed during the coadministration of benztropine and selective serotonin reuptake inhibitors (SSRIs). The mechanism of this potential interaction, if any, has not been determined. There have only been isolated case reports, and concomitant neuroleptic use was common.
MANAGEMENT: Until further data are available, it may be appropriate to monitor patients for evidence of delirium or other unusual psychiatric reactions when benztropine is given with SSRIs, especially if neuroleptic therapy is also administered.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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