bactramycin and Erythrocin lactobionate Interactions

Interactions between bactramycin(lincomycin) and Erythrocin lactobionate (erythromycin)

erythromycin and lincomycin (Moderate Drug-Drug)

GENERALLY AVOID: Lincomycin derivatives and erythromycin have antagonistic effects in vitro. The mechanism is competitive binding of the 50S ribosomal subunit.

MANAGEMENT: Clindamycin or lincomycin should not be used concurrently with erythromycin.