baclofen and Xyrem Interactions

Interactions between baclofen and Xyrem (sodium oxybate)

baclofen and sodium oxybate (Major Drug-Drug)

GENERALLY AVOID: The central nervous system (CNS)- and respiratory-depressant effects of sodium oxybate may be potentiated by other agents with CNS-depressant effects.

MANAGEMENT: Agents with CNS depressant effects should be avoided during sodium oxybate therapy.