b-12-dots and K tab Interactions

Interactions between b-12-dots(cyanocobalamin) and K tab (potassium chloride)

potassium chloride and cyanocobalamin (Minor Drug-Drug)

Limited data suggest that orally administered potassium chloride may decrease the gastrointestinal absorption of vitamin B12. The mechanism is believed to be a reduction in ileal pH by potassium chloride, which significantly decreases the activity of intrinsic factor that is necessary for vitamin B12 absorption. However, the interaction should rarely lead to clinically significant deficiency because the body (primarily the liver) usually has a copious supply of vitamin B12 that can sustain a person for several years in the absence of adequate intake. As for the treatment of B12 deficiency-related anemia, parenteral or intranasal administration is generally the preferred route, which would bypass the potential interaction.