Drug interactions between Ativan and quetiapine
| Results for the following 2 drugs: |
|---|
| Ativan (lorazepam) |
| quetiapine |
Interactions between your selected drugs
lorazepam ↔ quetiapine
Applies to:Ativan (lorazepam) and quetiapine
MONITOR: The oral clearance of a single dose of lorazepam has been reported to be decreased by 20% when taken concomitantly with quetiapine. The mechanism of action is unknown. Additionally, quetiapine may enhance the CNS effects of lorazepam.
MANAGEMENT: The clinician may consider closer clinical monitoring of the patient for lorazepam toxicity if quetiapine and lorazepam are coadministered. Patients should be advised to notify their physician if they experience symptoms such as excessive sedation, confusion, dizziness, or incoordination.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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