Drug interactions between atazanavir and disulfiram
Results for the following 2 drugs: |
|
|---|---|
| atazanavir | |
| disulfiram | |
Interactions between your selected drugs
disulfiram ⇔ atazanavir
Applies to: disulfiram and atazanavir
MONITOR: Coadministration with atazanavir may increase the plasma concentrations of drugs that are primarily metabolized by CYP450 1A2 and/or 2C9. The mechanism is decreased clearance due to competitive inhibition of CYP450 1A2 and 2C9 activity by atazanavir.
MANAGEMENT: Caution is advised if atazanavir must be used concomitantly with medications that undergo metabolism by CYP450 1A2 and/or 2C9, particularly those with a narrow therapeutic range. Dosage adjustments as well as clinical and laboratory monitoring may be appropriate for some drugs whenever atazanavir is added to or withdrawn from therapy.
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