Drug interactions between Atapryl and disulfiram
Results for the following 2 drugs: |
|
|---|---|
| Atapryl (selegiline) | |
| disulfiram | |
Interactions between your selected drugs
selegiline ⇔ disulfiram
Applies to: Atapryl (selegiline) and disulfiram
MONITOR: Delirium has been observed during the coadministration of disulfiram and monoamine oxidase inhibitors (MAOIs). The mechanism of interaction has not been determined. Clinical evidence is limited to one case report in which tranylcypromine was added to a regimen including disulfiram and lithium.
MANAGEMENT: Until further data are available, it may be appropriate to monitor patients for evidence of delirium or other unusual psychiatric reactions when disulfiram is given with MAOIs or other agents that possess MAOI activity (e.g., furazolidone, linezolid, procarbazine). If symptoms occur, the MAOI should not be discontinued abruptly because of the risk of withdrawal symptoms.
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