Drug interactions between Aspirin Low Strength and sotalol
Results for the following 2 drugs: |
|
|---|---|
| Aspirin Low Strength (aspirin) | |
| sotalol | |
Interactions between your selected drugs
aspirin ⇔ sotalol
Applies to: Aspirin Low Strength (aspirin) and sotalol
High doses of salicylates may blunt the antihypertensive effects of beta-blockers. The proposed mechanism is inhibition of prostaglandin synthesis. Low-dose aspirin does not appear to affect blood pressure. In addition, beta-blockers may exert an antiplatelet effect, which may be additive with the effects of some salicylates. Metoprolol may also increase aspirin absorption and/or plasma concentrations of salicylates; however, the clinical significance of this effect is unknown. Data have been conflicting. Until more information is available, patients who require concomitant therapy should be monitored for altered antihypertensive response whenever a salicylate is introduced or discontinued, or when its dosage is modified.
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