Drug interactions between Aspirin Low Strength and hydralazine/isosorbide dinitrate
| Results for the following 2 drugs: |
|---|
| Aspirin Low Strength (aspirin) |
| hydralazine/isosorbide dinitrate |
Interactions between your selected drugs
hydralazine ↔ aspirin
Applies to:hydralazine/isosorbide dinitrate and Aspirin Low Strength (aspirin)
MONITOR: Nonsteroidal anti-inflammatory drugs (NSAIDs) may attenuate the antihypertensive effect of hydralazine and dihydralazine. This interaction suggests that prostaglandins play a pivotal role in the vasodilatory effects of hydralazine. However, data have been conflicting.
MANAGEMENT: Recommended management consists of monitoring the antihypertensive effectiveness of hydralazine or dihydralazine during therapy, increasing the dosage as necessary, or decreasing or substituting another drug for the NSAID.
See also...
- Hydralazine/isosorbide dinitrate Drug Interactions
- hydralazine and isosorbide dinitrate General Consumer Information
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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