Drug interactions between Aspirin Low Strength and Cartia XT
Results for the following 2 drugs: |
|
|---|---|
| Aspirin Low Strength (aspirin) | |
| Cartia XT (diltiazem) | |
Interactions between your selected drugs
diltiazem ⇔ aspirin
Applies to: Cartia XT (diltiazem) and Aspirin Low Strength (aspirin)
MONITOR: Several case reports have suggested that verapamil and aspirin may have synergistic antiplatelet effects. The mechanism of this interaction has not been fully elucidated. Also, one study of five patients has suggested that aspirin may reverse the antihypertensive effect of verapamil. The mechanism may be related to antagonism of the effect of verapamil on prostacyclin. Diltiazem has been shown to interact with aspirin in a similar manner.
MANAGEMENT: Close observation for prolonged bleeding time and reduced antihypertensive effect is recommended if these drugs must be used together. Patients should be advised to notify their physician if they experience unusual bleeding, bruising, or petechiae. Aspirin should be discontinued if an interaction is suspected.
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