Drug interactions between Analgesic Balm and Miradon
| Results for the following 2 drugs: |
|---|
| Analgesic Balm (methyl salicylate topical) |
| Miradon (anisindione) |
Interactions between your selected drugs
anisindione ↔ methyl salicylate
Applies to:Miradon (anisindione) and Analgesic Balm (methyl salicylate topical)
GENERALLY AVOID: Methyl salicylate may be absorbed systemically following topical administration and may potentiate the effects of oral anticoagulants. Salicylates interfere with the action of vitamin K and induce a dose-dependent alteration in hepatic synthesis of coagulation factors VII, IX and X, occasionally increasing the prothrombin time. Altered coagulation parameters and/or bleeding have been reported in patients stabilized on warfarin following the use of topical analgesic preparations containing methyl salicylate.
MANAGEMENT: Patients treated with oral anticoagulants should avoid or limit self-medication with these products. Systemic absorption of topical medication may be increased with frequent applications; use of large quantities or over large areas of skin; use of ointment-based formulations; and use of occlusive dressings or heating pads over application areas. Patients should be advised to promptly report any signs of bleeding to their physician, including pain, swelling, headache, dizziness, weakness, prolonged bleeding from cuts, increased menstrual flow, vaginal bleeding, nosebleeds, bleeding of gums from brushing, unusual bleeding or bruising, red or brown urine, or red or black stools. Patients should also be counseled to avoid any other over-the-counter salicylate products.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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