amphocin and Alkeran i v Interactions

Interactions between amphocin(amphotericin B) and Alkeran i v (melphalan)

amphotericin B and melphalan (Moderate Drug-Drug)

MONITOR: The concurrent or sequential use of two or more potentially nephrotoxic or neurotoxic drugs may increase the risk of toxicity. Patients who are elderly, debilitated, dehydrated, or who have pre-existing renal dysfunction may have a higher risk of developing adverse reactions.

MANAGEMENT: Close clinical and laboratory monitoring of renal and neurologic function and drug serum concentrations (if clinically appropriate) is recommended.