Drug interactions between amiodarone and Coreg
Results for the following 2 drugs: |
|
|---|---|
| amiodarone | |
| Coreg (carvedilol) | |
Interactions between your selected drugs
amiodarone ⇔ carvedilol
Applies to: amiodarone and Coreg (carvedilol)
MONITOR: Additive effects of severe bradycardia, cardiac arrest, and ventricular fibrillation may occur in patients administered amiodarone and beta blockers. The mechanism may be related to additive slowing in AV conduction. In addition, amiodarone may inhibit the first pass hepatic metabolism of some beta blockers. However, a post hoc meta analysis suggests that the addition of amiodarone in patients in whom it is indicated, who are recovering from a recent myocardial infarction, and who are already receiving beta-blockers decreases the incidence of cardiac or arrhythmic death.
MANAGEMENT: Clinical monitoring of patient hemodynamic status and response is recommended.
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