Drug interactions between alvimopan and tramadol
Results for the following 2 drugs: |
|
|---|---|
| alvimopan | |
| tramadol | |
Interactions between your selected drugs
tramadol ⇔ alvimopan
Applies to: tramadol and alvimopan
CONTRAINDICATED: Recent exposure to opioids can increase the sensitivity to mu opioid receptor antagonists.
MANAGEMENT: The use of alvimopan is contraindicated in patients who have received therapeutic doses of opioids for more than 7 consecutive days immediately prior to alvimopan administration. Caution is advised in patients who have received more than 3 doses of an opioid within the week prior to surgery, as these patients were not studied in the postoperative ileus clinical trials. Patients with recent exposure to opioids should be monitored for increased adverse effects such as abdominal pain, nausea and vomiting, and diarrhea.
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