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Drug Interactions between aldesleukin and DTIC-Dome

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

dacarbazine aldesleukin

Applies to: DTIC-Dome (dacarbazine) and aldesleukin

Using aldesleukin together with dacarbazine may increase the risk of a potentially fatal condition known as tumor lysis syndrome, which is associated with certain electrolyte and chemical imbalances in the blood and kidney failure. In addition, using these medications together or one after the other has occasionally been associated with serious allergic reactions. You should be monitored closely by your doctor for signs of a reaction so that emergency treatment may be administered if necessary. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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