Drug Interactions

Drug interactions between Aerolate JR and Synthroid

Results for the following 2 drugs:

Aerolate JR (theophylline)
Synthroid (levothyroxine)

Interactions between your selected drugs

theophylline ⇔ levothyroxine

Applies to: Aerolate JR (theophylline) and Synthroid (levothyroxine)

MONITOR: The metabolism of theophylline is directly related to thyroid function. Theophylline clearance is decreased in hypothyroid patients and increased in hyperthyroid patients. Toxicity or subtherapeutic levels may occur. Similar interactions may occur with other methylxanthines.

MANAGEMENT: When thyroid hormone dosage is instituted, discontinued, or changed, close observation for altered theophylline effect and serum concentrations is recommended. Patients should be advised to notify their physician if they experience a worsening of their respiratory symptoms, or any signs of theophylline toxicity including nausea, vomiting, diarrhea, headache, restlessness, insomnia, or irregular heartbeats.

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