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Drug Interactions between Adacel (Tdap) and Tabloid

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

tetanus toxoid thioguanine

Applies to: Adacel (Tdap) (diphtheria toxoid / pertussis, acellular / tetanus toxoid) and Tabloid (thioguanine)

If you are currently being treated or have recently been treated with thioguanine, you should let your doctor know before receiving tetanus toxoid. Depending on the dose and length of time you have been on thioguanine, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of thioguanine therapy. If you have recently been vaccinated with tetanus toxoid, your doctor may choose to postpone treatment with thioguanine for a couple of weeks or more. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

thioguanine diphtheria toxoid

Applies to: Tabloid (thioguanine) and Adacel (Tdap) (diphtheria toxoid / pertussis, acellular / tetanus toxoid)

If you are currently being treated or have recently been treated with thioguanine, you should let your doctor know before receiving diphtheria toxoid. Depending on the dose and length of time you have been on thioguanine, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of thioguanine therapy. If you have recently been vaccinated with diphtheria toxoid, your doctor may choose to postpone treatment with thioguanine for a couple of weeks or more. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

thioguanine pertussis, acellular

Applies to: Tabloid (thioguanine) and Adacel (Tdap) (diphtheria toxoid / pertussis, acellular / tetanus toxoid)

If you are currently being treated or have recently been treated with thioguanine, you should let your doctor know before receiving pertussis, acellular. Depending on the dose and length of time you have been on thioguanine, you may have a reduced response to the vaccine. In some situations, your doctor may want to delay vaccination to give your body time to recover from the effects of thioguanine therapy. If you have recently been vaccinated with pertussis, acellular, your doctor may choose to postpone treatment with thioguanine for a couple of weeks or more. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

thioguanine food

Applies to: Tabloid (thioguanine)

Thioguanine may cause liver problems, and using it with other medications that can also affect the liver such as ethanol may increase that risk. You should avoid or limit the use of alcohol while being treated with these medications. Call your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.