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Sudafed PE Severe Cold Interactions

There are 648 drugs known to interact with Sudafed PE Severe Cold (acetaminophen/diphenhydramine/phenylephrine), along with 15 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 49 are major, 585 are moderate, and 14 are minor.

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Most frequently checked interactions

View interaction reports for Sudafed PE Severe Cold (acetaminophen / diphenhydramine / phenylephrine) and the medicines listed below.

Sudafed PE Severe Cold alcohol/food interactions

There are 2 alcohol/food interactions with Sudafed PE Severe Cold (acetaminophen / diphenhydramine / phenylephrine).

Sudafed PE Severe Cold disease interactions

There are 15 disease interactions with Sudafed PE Severe Cold (acetaminophen / diphenhydramine / phenylephrine) which include:


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.