abacavir and Agenerase Interactions

Interactions between abacavir and Agenerase (amprenavir)

abacavir and amprenavir (Minor Drug-Drug)

Coadministration of amprenavir with abacavir results in increased blood levels of amprenavir. Average amprenavir levels increased 29% in the area under the time concentration curve during concomitant administration. The clinical significance is unknown. Patients receiving this combination should be monitored for altered efficacy and safety.