Tricyclic antidepressants
A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.
Tricyclic antidepressants (TCAs) act by inhibiting reuptake of norepinephrine and serotonin by blocking the transporters responsible for reuptake of these neurotransmitters. This inhibition elevates the concentration of neurotransmitters in the synapses and triggers further neurotransmission.
Tricyclic antidepressants are used to treat depression, bipolar disorder, anxiety, obsessive-compulsive disorder and other mood disorders. They are also effective as analgesics so are used to treat chronic pain and used for migraine prophylaxis.
| Drug Name |
Reviews | Avg. Ratings |
|
|---|---|---|---|
| amoxapine systemic (Pro, More...) |
2 Review(s) |
Rate It! | 10 |
| desipramine systemic (Pro, More...) |
5 Review(s) |
Rate It! | 9.0 |
| imipramine systemic (Pro, More...) |
13 Review(s) |
Rate It! | 8.2 |
| trimipramine systemic (Pro, More...) |
1 Review(s) |
Rate It! | 8.0 |
| clomipramine systemic (Pro, More...) |
19 Review(s) |
Rate It! | 7.7 |
| nortriptyline systemic (Pro, More...) |
64 Review(s) |
Rate It! | 7.7 |
| doxepin systemic (Pro, More...) |
79 Review(s) |
Rate It! | 7.6 |
| amitriptyline systemic (Pro, More...) |
198 Review(s) |
Rate It! | 7.5 |
| protriptyline systemic (Pro, More...) |
1 Review(s) |
Rate It! | 7.0 |
See also
Medical conditions associated with tricyclic antidepressants:
- ADHD
- Anxiety
- Anxiety and Stress
- Burning Mouth Syndrome
- Cyclic Vomiting Syndrome
- Depression
- Diabetic Nerve Damage
- Dysautonomia
- Dysthymia
- Fibromyalgia
- Hyperhidrosis
- Insomnia
- Interstitial Cystitis
- Irritable Bowel Syndrome
- Migraine Prevention
- Neuralgia
- Neurosis
- Neurotic Depression
- Night Terrors
- Obsessive Compulsive Disorder
- Pain
- Panic Disorder
- Persisting Pain, Shingles
- Post Traumatic Stress Disorder
- Primary Nocturnal Enuresis
- Reflex Sympathetic Dystrophy Syndrome
- Smoking Cessation
- Somatoform Pain Disorder
- Tinnitus
- Urinary Incontinence
- Urticaria
- Vulvodynia

