A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.
Purine nucleosides are antiviral agents that have selective activity against herpes simplex virus types 1 (cold sores) and 2 (genital herpes) and varicella zoster virus (chicken pox).
The purine nucleoside molecule is converted to a monophosphate by viral thymidine kinases. The monophosphate is then converted to diphosphate and then into a triphosphate form by cellular enzymes. The triphosphate form blocks the replication of viral DNA by inhibiting viral DNA polymerase and terminating the growing viral DNA chain.
Purine nucleosides are more potent against the viral enzymes than the host enzymes.
|Drug Name ( View by: Brand | Generic )||Reviews||Ratings|
|ganciclovir systemic (Pro, More...)
|valacyclovir systemic (Pro, More...)
|acyclovir systemic (Pro, More...)
|famciclovir systemic (Pro, More...)
|ribavirin systemic (Pro, More...)
|cidofovir systemic (Pro, More...)
|valganciclovir systemic (Pro, More...)
Medical conditions associated with purine nucleosides:
- CMV Retinitis
- Cold Sores
- Cytomegalovirus Infection
- Hepatitis C
- Herpes Simplex
- Herpes Simplex Encephalitis
- Herpes Simplex, Mucocutaneous/Immunocompetent Host
- Herpes Simplex, Mucocutaneous/Immunocompromised Host
- Herpes Simplex, Suppression
- Herpes Zoster
- Infectious Mononucleosis
- Multiple Sclerosis
- Ramsay Hunt Syndrome
- Respiratory Syncytial Virus
- Smallpox Vaccine Reaction