A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.
Protease inhibitors are synthetic drugs that inhibit the action of HIV-1 protease, an enzyme that cleaves two precursor proteins into smaller fragments. These fragments are needed for viral growth, infectivity and replication. Protease inhibitors bind to the active site of the protease enzyme and prevent the maturation of the newly produced virions so that they remain non-infectious.
Protease inhibitors are used in the treatment of human immunodeficiency virus (HIV infection) and acquired immune deficiency syndrome (AIDS).
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Data sources include Micromedex® (updated Aug 13th, 2014), Cerner Multum™ (updated Aug 17th, 2014), Wolters Kluwer™ (updated Aug 4th, 2014) and others. To view content sources and attributions, refer to our editorial policy.