Bisphosphonates

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Bisphosphonates are drugs that inhibit mineralization or resorption of the bone by blocking the action of osteoclasts. Bisphosphonates are enzyme-resistant analogues of pyrophosphate, which normally inhibits mineralization in the bone. Their effect is dose dependent and they reduce the turnover of bone by inhibiting recruitment and promoting apoptosis of osteoclasts. Bisphosphonates are used to treat postmenopausal and glucocorticoid induced osteoporosis, Paget's disease of bone and malignant hypercalcemia. There are a few bisphosphonates available and one might work better for a particular condition, than the other.

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Drug Name DownUp( View by: Brand | Generic ) Reviews Ratings DownUp
alendronate / cholecalciferol systemic (Pro, More...)
0 reviews
   
9.5
etidronate systemic (Pro, More...)
0 reviews
   
7.0
zoledronic acid systemic (Pro, More...)
34 reviews
   
6.9
alendronate systemic (Pro, More...)
15 reviews
   
5.3
ibandronate systemic (Pro, More...)
23 reviews
   
5.0
risedronate systemic (Pro, More...)
15 reviews
   
4.6
calcium carbonate / risedronate systemic (Pro, More...)
1 review
   
3.0
pamidronate systemic (Pro, More...)
0 reviews
   
0.0
tiludronate systemic (Pro, More...)
0 reviews
   
0.0
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