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Zolmitriptan Dosage

Medically reviewed by Drugs.com. Last updated on Sep 6, 2023.

Applies to the following strengths: 5 mg; 2.5 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Migraine

Oral:

Maximum single dose: 5 mg
Maximum daily dose: 10 mg in a 24-hour period

Orally Disintegrating Tablets:
Maximum single dose: 5 mg
Maximum daily dose: 10 mg in a 24-hour period

Nasal Spray:
Maximum single dose: 5 mg
Maximum daily dose: 10 mg in a 24-hour period

Comments:

Use: For the acute treatment of migraine with or without aura.

Usual Pediatric Dose for Migraine

Age 12 years and older:

Nasal Spray:

Maximum single dose: 5 mg
Maximum daily dose: 10 mg in a 24-hour period

Comments:

Use: For the acute treatment of migraine with or without aura.

Renal Dose Adjustments

Use caution; No adjustment recommended

Liver Dose Adjustments

Mild Hepatic Impairment: No dosage adjustment recommended

Moderate to Severe Hepatic Impairment:
Oral tablets:
Initial dose: 1.25 mg (obtained by breaking oral tablet in one-half)
Maximum daily dose should not exceed 5 mg per day

Oral disintegrating tablets (ODT): Not recommended for initial dosing as ODT should not be broken in half
Nasal Spray: Not recommended

Dose Adjustments

Elderly Patients:


Concomitant use with Cimetidine:

Precautions

Safety and efficacy of nasal spray have not been established in patients younger than 12 years.
Safety and efficacy of oral tablets and oral disintegrating tablets have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Oral:

Oral disintegrating tablet

Nasal:

General:

Monitoring:

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.