This dosage information may not include all the information needed to use Vilazodone safely and effectively. See additional information for Vilazodone.
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Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Depression
For major depressive disorder (MDD):
Initial dose of 10 mg orally once daily for 7 days, followed by 20 mg orally once daily for an additional 7 days, and then increased to 40 mg orally once daily.
Vilazodone should be taken with food. Administration without food can result in inadequate drug concentrations and may diminish effectiveness.
When discontinuing treatment, reduce the dose gradually.
Renal Dose Adjustments
No dose adjustment is recommended in patients with mild, moderate, or severe renal impairment.
Liver Dose Adjustments
No dose adjustment is recommended in patients with mild or moderate hepatic impairment. Vilazodone has not been studied in severe hepatic impairment.
Data not available
At least 14 days should elapse between discontinuation of an MAOI intended to treat psychiatric disorders and initiation of therapy with vilazodone. Conversely, at least 14 days should be allowed after stopping vilazodone before starting an MAOI intended to treat psychiatric disorders.