Terbutaline Dosage

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Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Asthma - Maintenance

Tablets: 5 mg orally 3 times a day at 6 hour intervals during waking hours. May decrease to 2.5 mg/dose if side effects are pronounced. Do not exceed 15 mg in 24 hours.

Inhalation aerosol: 2 inhalations separated by 60 seconds every 4 to 6 hours. Do not repeat more often than every 4 to 6 hours.

Usual Adult Dose for Premature Labor

Tablets: 2.5 to 7.5 mg orally every 6 hours. Therapy should be continued until 36 to 37 weeks gestation.

Continuous intravenous infusion: 10 to 25 mcg/min. Therapy should be continued until labor has been arrested. Maximum dose 80 mcg/min.

Subcutaneous injection: 0.25 mg every 6 hours. Subcutaneous therapy should be continued until labor has been arrested.

Usual Adult Dose for Asthma - Acute

Inhalation aerosol: 2 inhalations separated by 60 seconds every 4 to 6 hours. Do not repeat more often than every 4 to 6 hours.

Subcutaneous Injection: 0.25 mg into the lateral deltoid area. A second 0.25 mg dose can be administered in 15 to 30 minutes if needed. Do not exceed 0.5 mg in 4 hours.

Continuous intravenous infusion: 0.08 to 6 mcg/kg/min.

Usual Pediatric Dose for Asthma - Acute

Subcutaneous Injection: 0.005 to 0.01 mg/kg/dose to a maximum dose of 0.4 mg every 15 to 20 minutes for 2 doses.

Nebulization: 0.01 to 0.03 mg/kg/dose with a minimum dose of 0.1 mg; maximum dose is 2.5 mg diluted with 1 to 2 mL of normal saline every 4 to 6 hours.

Continuous intravenous infusion: 0.08 to 6 mcg/kg/min.

> 12 years:
Inhalation aerosol: 2 inhalations separated by 60 seconds every 4 to 6 hours. Do not repeat more often than every 4 to 6 hours.

Subcutaneous Injection: 0.25 mg into the lateral deltoid area. A second 0.25 mg dose can be administered in 15-30 minutes if needed. Maximum dose 0.5 mg in 4 hours.

Usual Pediatric Dose for Asthma - Maintenance

< 12 years:
Tablets: 0.05 mg/kg/day divided into three doses. Gradually increase to 0.15 mg/kg/day. Maximum dose is 5 mg per day.

>=12 years:
Inhalation aerosol: 2 inhalations separated by 60 seconds every 4 to 6 hours. Do not repeat more often than every 4 to 6 hours.

>=12 <15 years:
Tablets: 2.5 mg orally every 6 to 8 hours. Do not exceed 7.5 mg in 24 hours

>=15 years:
Tablets: 2.5 mg to 5 mg orally every 6 to 8 hours. Do not exceed 15 mg in 24 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Terbutaline is not approved by the FDA for use as a tocolytic agent. Although terbutaline and other beta-agonists have been shown to be effective in arresting episodes of premature labor, there are few studies which evaluate its use for maintenance therapy after successful treatment of an episode of premature labor. A meta-analysis of those few studies did not support its use for maintenance therapy.

Dialysis

Data not available

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