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Tamoxifen Dosage

Medically reviewed by Drugs.com. Last updated on Jun 14, 2023.

Applies to the following strengths: 10 mg; 20 mg; 10 mg/5 mL

Usual Adult Dose for Breast Cancer

Metastatic breast cancer in women and men:
20 to 40 mg orally daily for 5 years; doses greater than 20 mg should be given in divided doses (morning and evening)

DCIS following breast surgery and radiation:
20 mg orally daily for 5 years

To reduce the incidence of breast cancer in women at high risk for breast cancer:
20 mg orally daily for 5 years

Comments:


Uses:

Usual Adult Dose for Breast Cancer - Adjuvant

20 mg orally once daily or 10 mg orally 2 times daily
Duration of therapy: Up to 5 years

Comments:


Use: For the treatment of node-positive breast cancer in postmenopausal women following total mastectomy or segmental mastectomy, axillary dissection, and breast irradiation

Usual Pediatric Dose for McCune-Albright Syndrome

Girls 2 to 10 years with McCune-Albright Syndrome and precocious puberty:
20 mg orally once daily
Duration of therapy: Up to 12 months

Use: McCune-Albright Syndrome; precocious puberty

Usual Pediatric Dose for Precocious Puberty

Girls 2 to 10 years with McCune-Albright Syndrome and precocious puberty:
20 mg orally once daily
Duration of therapy: Up to 12 months

Use: McCune-Albright Syndrome; precocious puberty

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

US BOXED WARNINGS:
Women with Ductal Carcinoma in Situ (DCIS) and Women at High Risk for Breast Cancer:

CONTRAINDICATIONS:

Safety and efficacy have not been established in male patients younger than 18 years.

Safety and efficacy have not been established in female patients younger than 2 years for McCune-Albright Syndrome and precocious puberty, or female patients 10 years to 18 years for McCune-Albright Syndrome and precocious puberty.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.