Suprax Dosage
Generic name: cefixime
Dosage form: powder, for oral suspension
See also:
This dosage information does not include all the information needed to use Suprax safely and effectively. See full prescribing information for Suprax.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Adults: The recommended dose of cefixime is 400 mg daily. This may be given as a 400 mg tablet daily or as 200 mg tablet every 12 hours. For the treatment of uncomplicated cervical/urethral gonococcal infections, a single oral dose of 400 mg is recommended.
Children: The recommended dose is 8 mg/kg/day of the suspension. This may be administered as a single daily dose or may be given in two divided doses, as 4 mg/kg every 12 hours.
| PEDIATRIC DOSAGE CHART |
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| 100 mg/5 mL |
200 mg/5 mL |
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| Patient Weight (kg) |
Dose/Day mg |
Dose/Day mL |
Dose/Day tsp of Suspension |
Dose/Day mL |
Dose/Day tsp of Suspension |
| 6.25 |
50 |
2.5 |
½ |
1.25 |
¼ |
| 12.5 |
100 |
5 |
1 |
2.5 |
½ |
| 18.75 |
150 |
7.5 |
1½ |
3.75 |
¾ |
| 25 |
200 |
10 |
2 |
5 |
1 |
| 31.25 |
250 |
12.5 |
2½ |
6.25 |
1¼ |
| 37.5 |
300 |
15 |
3 |
7.5 |
1½ |
Children weighing more than 50 kg or older than 12 years should be treated with the recommended adult dose.
Otitis media should be treated with the suspension. Clinical studies of otitis media were conducted with the suspension, and the suspension results in higher peak blood levels than the tablet when administered at the same dose. Therefore, the tablet should not be substituted for the suspension in the treatment of otitis media. (See CLINICAL PHARMACOLOGY.)
Efficacy and safety in infants aged less than six months have not been established.
In the treatment of infections due to S. pyogenes, a therapeutic dosage of Suprax should be administered for at least 10 days.
Renal Impairment
Suprax may be administered in the presence of impaired renal function. Normal dose and schedule may be employed in patients with creatinine clearances of 60 mL/min or greater. Patients whose clearance is between 21 and 60 mL/min or patients who are on renal hemodialysis may be given 75% of the standard dosage at the standard dosing interval (i.e., 300 mg daily). Patients whose clearance is < 20 mL/min, or patients who are on continuous ambulatory peritoneal dialysis may be given half the standard dosage at the standard dosing interval (i.e., 200 mg daily). Neither hemodialysis nor peritoneal dialysis remove significant amounts of drug from the body.
| Strength |
Bottle Size |
Reconstitution Directions |
| 100 mg/5 mL and 200 mg/5 mL |
100 mL |
To reconstitute, suspend with 68 mL water. Method: Tap the bottle several times to loosen powder contents prior to reconstitution. Add approximately half the total amount of water for reconstitution and shake well. Add the remainder of water and shake well. |
| 100 mg/5 mL and 200 mg/5 mL |
75 mL |
To reconstitute, suspend with 51 mL water. Method: Tap the bottle several times to loosen powder contents prior to reconstitution. Add approximately half the total amount of water for reconstitution and shake well. Add the remainder of water and shake well. |
| 100 mg/5 mL and 200 mg/5 mL |
50 mL |
To reconstitute, suspend with 34 mL water. Method: Tap the bottle several times to loosen powder contents prior to reconstitution. Add approximately half the total amount of water for reconstitution and shake well. Add the remainder of water and shake well. |
| 200 mg/5 mL |
37.5 mL |
To reconstitute, suspend with 26 mL water. Method: Tap the bottle several times to loosen powder contents prior to reconstitution. Add approximately half the total amount of water for reconstitution and shake well. Add the remainder of water and shake well. |
| 200 mg/5 mL |
25 mL |
To reconstitute, suspend with 17 mL water. Method: Tap the bottle several times to loosen powder contents prior to reconstitution. Add approximately half the total amount of water for reconstitution and shake well. Add the remainder of water and shake well. |
After reconstitution the suspension may be kept for 14 days either at room temperature, or under refrigeration, without significant loss of potency. Keep tightly closed. Shake well before using. Discard unused portion after 14 days.
