Primsol Oral Solution Dosage

Generic name: TRIMETHOPRIM HYDROCHLORIDE 50mg in 5mL
Dosage form: oral solution
Drug class: Urinary anti-infectives

Medically reviewed by Drugs.com. Last updated on Nov 30, 2023.

Acute Otitis Media in Pediatric Patients

The recommended dose for pediatric patients with acute otitis media is 10 mg/kg trimethoprim per 24 hours, given in divided doses every 12 hours for 10 days. The following table is a guideline for the attainment of this dosage:

Pediatric patients 6 months of age or older:
Weight		Dose (every 12 hours)
lb	kg	tsp	mL
11	5	½	2.5
22	10	1	5
33	15	1½	7.5
44	20	2	10
55	25	2½	12.5
66	30	3	15
77	35	3½	17.5
≥88	≥40	4	20

Uncomplicated Urinary Tract Infections

The usual oral adult dosage is 100 mg (10 mL) every 12 hours or 200 mg (20 mL) every 24 hours, each for 10 days.

Patients with Impaired Renal Function

The use of trimethoprim in patients with a creatinine clearance of less than 15 mL/min is not recommended. Patients with a creatinine clearance of 15 to 30 mL/min should receive half the dose recommended for patients of the same age with normal renal function.