Prevacid Dosage

Generic name: lansoprazole
Dosage form: capsule, delayed release, tablet, orally disintegrating, delayed release

This dosage information does not include all the information needed to use Prevacid safely and effectively. See full prescribing information for Prevacid.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

PREVACID is available as a capsule and an orally disintegrating tablet, and is available in 15 mg and 30 mg strengths. Directions for use specific to the route and available methods of administration for each of these dosage forms is presented below. PREVACID should be taken before eating. PREVACID products SHOULD NOT BE CRUSHED OR CHEWED. In the clinical trials, antacids were used concomitantly with PREVACID.

Recommended Dose

Indication Recommended Dose Frequency
*
Please refer to amoxicillin and clarithromycin full prescribing information for CONTRAINDICATIONS and WARNINGS, and for information regarding dosing in elderly and renally-impaired patients.
Controlled studies did not extend beyond indicated duration.
For patients who do not heal with PREVACID for 8 weeks (5 to 10%), it may be helpful to give an additional 8 weeks of treatment. If there is a recurrence of erosive esophagitis, an additional 8 week course of PREVACID may be considered.
§
The PREVACID dose was increased (up to 30 mg twice daily) in some pediatric patients after 2 or more weeks of treatment if they remained symptomatic. For pediatric patients unable to swallow an intact capsule please see Administration Options.
Varies with individual patient. Recommended adult starting dose is 60 mg once daily. Doses should be adjusted to individual patient needs and should continue for as long as clinically indicated. Dosages up to 90 mg twice daily have been administered. Daily dose of greater than 120 mg should be administered in divided doses. Some patients with Zollinger-Ellison Syndrome have been treated continuously with PREVACID for more than 4 years.

Duodenal Ulcers

  Short-Term Treatment

15 mg

Once daily for 4 weeks

  Maintenance of Healed

15 mg

Once daily

H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence*

  Triple Therapy:

    PREVACID

30 mg

Twice daily (q12h) for 10 or 14 days

    Amoxicillin

1 gram

Twice daily (q12h) for 10 or 14 days

    Clarithromycin

500 mg

Twice daily (q12h) for 10 or 14 days

  Dual Therapy:

    PREVACID

30 mg

Three times daily (q8h) for 14 days

    Amoxicillin

1 gram

Three times daily (q8h) for 14 days

Benign Gastric Ulcer

  Short-Term Treatment

30 mg

Once daily for up to 8 weeks

NSAID-associated Gastric Ulcer

  Healing

30 mg

Once daily for 8 weeks

  Risk Reduction

15 mg

Once daily for up to 12 weeks

Gastroesophageal Reflux Disease (GERD)

  Short-Term Treatment of Symptomatic GERD

15 mg

Once daily for up to 8 weeks

  Short-Term Treatment of Erosive Esophagitis

30 mg

Once daily for up to 8 weeks

Pediatric

(1 to 11 years of age)
Short-Term Treatment of Symptomatic GERD and Short-Term Treatment of Erosive Esophagitis

  ≤ 30 kg

15 mg

Once daily for up to 12 weeks§

  > 30 kg

30 mg

Once daily for up to 12 weeks§

(12 to 17 years of age)
Short-Term Treatment of Symptomatic GERD

  Nonerosive GERD

15 mg

Once daily for up to 8 weeks

  Erosive Esophagitis

30 mg

Once daily for up to 8 weeks

Maintenance of Healing of Erosive Esophagitis

15 mg

Once daily

Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome

60 mg

Once daily

Patients should be instructed that if a dose is missed, it should be taken as soon as possible. However, if the next scheduled dose is due, the patient should not take the missed dose, and should be instructed to take the next dose on time. Patients should be instructed not to take 2 doses at one time to make up for a missed dose.

Special Populations

Renal impairment patients and geriatric patients do not require dosage adjustment. However, consider dose adjustment in patients with severe liver impairment [see Use in Specific Populations (8.5, 8.6 and 8.7)].

Important Administration Information

Administration Options

PREVACID Delayed-Release Capsules – Oral Administration

PREVACID Delayed-Release Capsules should be swallowed whole.
Alternatively, for patients who have difficulty swallowing capsules, PREVACID Delayed-Release Capsules can be opened and administered as follows:
∘
Open capsule.
∘
Sprinkle intact granules on one tablespoon of either applesauce, ENSURE pudding, cottage cheese, yogurt or strained pears.
∘
Swallow immediately.
PREVACID Delayed-Release Capsules may also be emptied into a small volume of either apple juice, orange juice or tomato juice and administered as follows:
∘
Open capsule.
∘
Sprinkle intact granules into a small volume of either apple juice, orange juice or tomato juice (60 mL – approximately 2 ounces).
∘
Mix briefly.
∘
Swallow immediately.
∘
To ensure complete delivery of the dose, the glass should be rinsed with two or more volumes of juice and the contents swallowed immediately.

PREVACID Delayed-Release Capsules – Nasogastric Tube (≥16 French) Administration

For patients who have a nasogastric tube in place, PREVACID Delayed-Release Capsules can be administered as follows:
∘
Open capsule.
∘
Mix intact granules into 40 mL of apple juice. DO NOT USE OTHER LIQUIDS.
∘
Inject through the nasogastric tube into the stomach.
∘
Flush with additional apple juice to clear the tube.

USE IN OTHER FOODS AND LIQUIDS HAS NOT BEEN STUDIED CLINICALLY AND IS THEREFORE NOT RECOMMENDED.

PREVACID SoluTab Delayed-Release Orally Disintegrating Tablets

PREVACID SoluTab should not be broken or cut.
PREVACID SoluTab should not be chewed.
∘
Place the tablet on the tongue and allow it to disintegrate, with or without water, until the particles can be swallowed.
∘
The tablet typically disintegrates in less than 1 minute.
∘
Alternatively, for children or other patients who have difficulty swallowing tablets, PREVACID SoluTab can be delivered in two different ways.
 
PREVACID SoluTab – Oral Syringe
 
For administration via oral syringe, PREVACID SoluTab can be administered as follows:
â–ª
Place a 15 mg tablet in oral syringe and draw up 4 mL of water, or place a 30 mg tablet in oral syringe and draw up 10 mL of water.
â–ª
Shake gently to allow for a quick dispersal.
â–ª
After the tablet has dispersed, administer the contents within 15 minutes.
â–ª
Refill the syringe with approximately 2 mL (5 mL for the 30 mg tablet) of water, shake gently, and administer any remaining contents.
 
PREVACID SoluTab Nasogastric Tube (≥8 French) Administration
 
For administration via a nasogastric tube, PREVACID SoluTab can be administered as follows:
â–ª
Place a 15 mg tablet in a syringe and draw up 4 mL of water, or place a 30 mg tablet in a syringe and draw up 10 mL of water.
â–ª
Shake gently to allow for a quick dispersal.
â–ª
After the tablet has dispersed, inject through the nasogastric tube into the stomach within 15 minutes.
â–ª
Refill the syringe with approximately 5 mL of water, shake gently, and flush the nasogastric tube.

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