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Prevacid Dosage
Generic name: lansoprazole
Dosage form: capsule, delayed release, tablet, orally disintegrating, delayed release
See also:
This dosage information does not include all the information needed to use Prevacid safely and effectively. See full prescribing information for Prevacid.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
PREVACID is available as a capsule and an orally disintegrating tablet, and is available in 15 mg and 30 mg strengths. Directions for use specific to the route and available methods of administration for each of these dosage forms is presented below. PREVACID should be taken before eating. PREVACID products SHOULD NOT BE CRUSHED OR CHEWED. In the clinical trials, antacids were used concomitantly with PREVACID.
Recommended Dose
| Indication | Recommended Dose | Frequency |
|---|---|---|
| ||
| Duodenal Ulcers | ||
| Short-Term Treatment | 15 mg | Once daily for 4 weeks |
| Maintenance of Healed | 15 mg | Once daily |
| H. pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence* | ||
| Triple Therapy: | ||
| PREVACID | 30 mg | Twice daily (q12h) for 10 or 14 days |
| Amoxicillin | 1 gram | Twice daily (q12h) for 10 or 14 days |
| Clarithromycin | 500 mg | Twice daily (q12h) for 10 or 14 days |
| Dual Therapy: | ||
| PREVACID | 30 mg | Three times daily (q8h) for 14 days |
| Amoxicillin | 1 gram | Three times daily (q8h) for 14 days |
| Benign Gastric Ulcer | ||
| Short-Term Treatment | 30 mg | Once daily for up to 8 weeks |
| NSAID-associated Gastric Ulcer | ||
| Healing | 30 mg | Once daily for 8 weeks† |
| Risk Reduction | 15 mg | Once daily for up to 12 weeks† |
| Gastroesophageal Reflux Disease (GERD) | ||
| Short-Term Treatment of Symptomatic GERD | 15 mg | Once daily for up to 8 weeks |
| Short-Term Treatment of Erosive Esophagitis | 30 mg | Once daily for up to 8 weeks‡ |
| Pediatric | ||
| (1 to 11 years of age) | ||
| ≤ 30 kg | 15 mg | Once daily for up to 12 weeks§ |
| > 30 kg | 30 mg | Once daily for up to 12 weeks§ |
| (12 to 17 years of age) | ||
| Nonerosive GERD | 15 mg | Once daily for up to 8 weeks |
| Erosive Esophagitis | 30 mg | Once daily for up to 8 weeks |
| Maintenance of Healing of Erosive Esophagitis | 15 mg | Once daily |
| Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome | 60 mg | Once daily¶ |
Patients should be instructed that if a dose is missed, it should be taken as soon as possible. However, if the next scheduled dose is due, the patient should not take the missed dose, and should be instructed to take the next dose on time. Patients should be instructed not to take 2 doses at one time to make up for a missed dose.
Special Populations
Renal impairment patients and geriatric patients do not require dosage adjustment. However, consider dose adjustment in patients with severe liver impairment [see Use in Specific Populations (8.5, 8.6 and 8.7)].
Important Administration Information
Administration Options
PREVACID Delayed-Release Capsules – Oral Administration
- •
- PREVACID Delayed-Release Capsules should be swallowed whole.
- •
- Alternatively, for patients who have difficulty swallowing capsules, PREVACID Delayed-Release Capsules can be opened and administered as follows:
- ∘
- Open capsule.
- ∘
- Sprinkle intact granules on one tablespoon of either applesauce, ENSURE pudding, cottage cheese, yogurt or strained pears.
- ∘
- Swallow immediately.
- •
- PREVACID Delayed-Release Capsules may also be emptied into a small volume of either apple juice, orange juice or tomato juice and administered as follows:
- ∘
- Open capsule.
- ∘
- Sprinkle intact granules into a small volume of either apple juice, orange juice or tomato juice (60 mL – approximately 2 ounces).
- ∘
- Mix briefly.
- ∘
- Swallow immediately.
- ∘
- To ensure complete delivery of the dose, the glass should be rinsed with two or more volumes of juice and the contents swallowed immediately.
PREVACID Delayed-Release Capsules – Nasogastric Tube (≥16 French) Administration
- •
- For patients who have a nasogastric tube in place, PREVACID Delayed-Release Capsules can be administered as follows:
- ∘
- Open capsule.
- ∘
- Mix intact granules into 40 mL of apple juice. DO NOT USE OTHER LIQUIDS.
- ∘
- Inject through the nasogastric tube into the stomach.
- ∘
- Flush with additional apple juice to clear the tube.
PREVACID SoluTab Delayed-Release Orally Disintegrating Tablets
- •
- PREVACID SoluTab should not be broken or cut.
- •
- PREVACID SoluTab should not be chewed.
- ∘
- Place the tablet on the tongue and allow it to disintegrate, with or without water, until the particles can be swallowed.
- ∘
- The tablet typically disintegrates in less than 1 minute.
- ∘
- Alternatively, for children or other patients who have difficulty swallowing tablets, PREVACID SoluTab can be delivered in two different ways.
- PREVACID SoluTab – Oral Syringe
- For administration via oral syringe, PREVACID SoluTab can be administered as follows:
- â–ª
- Place a 15 mg tablet in oral syringe and draw up 4 mL of water, or place a 30 mg tablet in oral syringe and draw up 10 mL of water.
- â–ª
- Shake gently to allow for a quick dispersal.
- â–ª
- After the tablet has dispersed, administer the contents within 15 minutes.
- â–ª
- Refill the syringe with approximately 2 mL (5 mL for the 30 mg tablet) of water, shake gently, and administer any remaining contents.
- PREVACID SoluTab – Nasogastric Tube (≥8 French) Administration
- For administration via a nasogastric tube, PREVACID SoluTab can be administered as follows:
- â–ª
- Place a 15 mg tablet in a syringe and draw up 4 mL of water, or place a 30 mg tablet in a syringe and draw up 10 mL of water.
- â–ª
- Shake gently to allow for a quick dispersal.
- â–ª
- After the tablet has dispersed, inject through the nasogastric tube into the stomach within 15 minutes.
- â–ª
- Refill the syringe with approximately 5 mL of water, shake gently, and flush the nasogastric tube.
